منابع مشابه
Ageing and vascular ageing.
There is an age related decline in various physiological processes. Vascular ageing is associated with changes in the mechanical and the structural properties of the vascular wall, which leads to the loss of arterial elasticity and reduced arterial compliance. Arterial compliance can be measured by different parameters like pulse wave velocity, augmentation index, and systemic arterial complian...
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We will never be perfect in achieving a diagnosis in every patient, and the challenge of geriatrics is how difficult it can be in some patients, and indeed, whether it is appropriate in others. An audit of our own ill-defined diagnoses showed that re-admission rates, at 1 month, were 10%, very similar to our better defined patients, and the great majority did not return to hospital within the n...
متن کاملHealthy ageing: ageing safely.
The population of the developed world is steadily ageing. In the European Union, approximately 22% of persons are over 60 years of age and this is projected to increase to more than 27% by the year 2020. This has major implications for health care resources and the productive workforce. Ageing is accompanied by a decline in the physiological reserve of all organ systems, compromising homeostasi...
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The ageing endothelium progressively loses its remarkable and crucial ability to maintain homeostasis of the vasculature, as it acquires a proinflammatory phenotype. Cellular and structural changes gradually accumulate in the blood vessels, and markedly in artery walls. Most changes in aged arteries are comparable to those occurring during the atherogenic process, the latter being more marked: ...
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Ageing is associated with functional, structural and mechanical changes in arteries that closely resemble the vascular alterations in hypertension. Characteristic features of large and small arteries that occur with ageing and during the development of hypertension include endothelial dysfunction, vascular remodelling, inflammation, calcification and increased stiffness. Arterial changes in you...
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ژورنال
عنوان ژورنال: Postgraduate Medical Journal
سال: 2006
ISSN: 0032-5473
DOI: 10.1136/pgmj.2005.036053